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N-Edited Guanine Isosteres

[Image: see text] Guanine is one out of five endogenous nucleobases and of key interest in drug discovery and chemical biology. Hitherto, the synthesis of guanine derivatives involves lengthy multistep sequential synthesis of low overall diversity, resulting in the quest for innovation. Using a “sin...

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Detalles Bibliográficos
Autores principales: Li, Xin, Romero, Marina Diguele, Tcaturian, Sona, Kurpiewska, Katarzyna, Dömling, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10367071/
https://www.ncbi.nlm.nih.gov/pubmed/37431831
http://dx.doi.org/10.1021/acs.joc.3c00467