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The cardioprotective effects of secoisolariciresinol diglucoside (flaxseed lignan) against cafeteria diet-induced cardiac fibrosis and vascular injury in rats: an insight into apelin/AMPK/FOXO3a signaling pathways

Introduction: Fast food is a major risk factor for atherosclerosis, a leading cause of morbidity and mortality in the Western world. Apelin, the endogenous adipokine, can protect against cardiovascular disease via activating its receptor, APJ. Concurrently, secoisolariciresinol diglucoside (SDG), a...

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Detalles Bibliográficos
Autores principales: Abdelwahab, Azza H., Negm, Amira M., Mahmoud, Eman S., Salama, Rania M., Schaalan, Mona F., El-Sheikh, Azza A. K., Ramadan, Basma K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10367100/
https://www.ncbi.nlm.nih.gov/pubmed/37497114
http://dx.doi.org/10.3389/fphar.2023.1199294