Granzyme-A deficiency attenuates experimental osteoarthritis in mice, but perforin deficiency does not

OBJECTIVES: This study aims to assess the development of osteoarthritis (OA) in granzyme A- (gzmA) and B- (gzmB) and perforin- (perf) knockout mice. MATERIALS AND METHODS: A total of 75 male and female C57BL/6 (eight to nine-week-old) mice were allocated to: gzmA-deficient (gzmA-/-) (11 females, 8 m...

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Detalles Bibliográficos
Autores principales: Calvo, Jorge, Santiago, Llipsy, Arias, Maykel, Pardo, Julián, Albareda, Jorge, Martínez-Lostao, Luis, García-Alvarez, Felícito
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bayçınar Medical Publishing 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10367147/
https://www.ncbi.nlm.nih.gov/pubmed/37462629
http://dx.doi.org/10.52312/jdrs.2023.892

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10367147/
https://www.ncbi.nlm.nih.gov/pubmed/37462629
http://dx.doi.org/10.52312/jdrs.2023.892

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