Deubiquitinase USP16 induces gouty arthritis via Drp1-dependent mitochondrial fission and NLRP3 inflammasome activation

BACKGROUND: Gouty arthritis is the most frequently diagnosed inflammatory arthritis worldwide. Dynamin-related protein 1 (Drp1), a regulator of mitochondrial fission, contributes to various inflammatory disorders via activating NLRP3 inflammasome. However, the biological role of Drp1 in gouty arthri...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Qingdong, Qiu, Hongbin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10367261/
https://www.ncbi.nlm.nih.gov/pubmed/37488647
http://dx.doi.org/10.1186/s13075-023-03095-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10367261/
https://www.ncbi.nlm.nih.gov/pubmed/37488647
http://dx.doi.org/10.1186/s13075-023-03095-7

Ejemplares similares