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Leptin/obR signaling exacerbates obesity-related neutrophilic airway inflammation through inflammatory M1 macrophages

BACKGROUND: Obesity-related asthma is a kind of nonallergic asthma with excessive neutrophil infiltration in the airways. However, the underlying mechanisms have been poorly elucidated. Among the adipokines related to obesity, leptin is related to the inflammatory response. However, little is unders...

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Detalles Bibliográficos
Autores principales: Wang, Yang, Wan, Rongjun, Hu, Chengping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10367413/
https://www.ncbi.nlm.nih.gov/pubmed/37488474
http://dx.doi.org/10.1186/s10020-023-00702-w