Cargando…
Leptin/obR signaling exacerbates obesity-related neutrophilic airway inflammation through inflammatory M1 macrophages
BACKGROUND: Obesity-related asthma is a kind of nonallergic asthma with excessive neutrophil infiltration in the airways. However, the underlying mechanisms have been poorly elucidated. Among the adipokines related to obesity, leptin is related to the inflammatory response. However, little is unders...
Autores principales: | Wang, Yang, Wan, Rongjun, Hu, Chengping |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10367413/ https://www.ncbi.nlm.nih.gov/pubmed/37488474 http://dx.doi.org/10.1186/s10020-023-00702-w |
Ejemplares similares
-
The Diagnostic and Therapeutic Role of Leptin and Its Receptor ObR in Glioblastoma Multiforme
por: Kinfe, Thomas M., et al.
Publicado: (2020) -
Effects of leptin on in vitro maturation, fertilization and embryonic cleavage after ICSI and early developmental expression of leptin (Ob) and leptin receptor (ObR) proteins in the horse
por: Lange Consiglio, Anna, et al.
Publicado: (2009) -
Energy homeostasis in leptin deficient Lep(ob/ob) mice
por: Skowronski, Alicja A., et al.
Publicado: (2017) -
Normalization of adiponectin concentrations by leptin replacement in ob/ob mice is accompanied by reductions in systemic oxidative stress and inflammation
por: Frühbeck, Gema, et al.
Publicado: (2017) -
Leptin Increases Particle-Induced Osteolysis in Female ob/obMice
por: Philbrick, Kenneth A., et al.
Publicado: (2018)