Purinergic receptor P2Y12 boosts autoimmune hepatitis through hexokinase 2-dependent glycolysis in T cells

Increasing evidence suggests that immunometabolism has started to unveil the role of metabolism in shaping immune function and autoimmune diseases. In this study, our data show that purinergic receptor P2Y12 (P2RY12) is highly expressed in concanavalin A (ConA)-induced immune hepatitis mouse model a...

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Detalles Bibliográficos
Autores principales: Zhuang, Wei, Liu, Xiucheng, Liu, Guangyu, Lv, Jie, Qin, Hao, Wang, Chun, Xie, Ling, Saimaier, Kaidireya, Han, Sanxing, Shi, Changjie, Hua, Qiuhong, Zhang, Ru, Du, Changsheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2023
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10367548/
https://www.ncbi.nlm.nih.gov/pubmed/37497007
http://dx.doi.org/10.7150/ijbs.85133

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10367548/
https://www.ncbi.nlm.nih.gov/pubmed/37497007
http://dx.doi.org/10.7150/ijbs.85133

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