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11β-Hydroxysteroid Dehydrogenase Type 1 Facilitates Osteoporosis by Turning on Osteoclastogenesis through Hippo Signaling

11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) is a key enzyme that transform cortisone to cortisol, which activates the endogenous glucocorticoid function. 11β-HSD1 has been observed to regulate skeletal metabolism, specifically within osteoblasts. However, the function of 11β-HSD1 in osteoclas...

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Detalles Bibliográficos
Autores principales: Li, Hanwen, Hu, Sihan, Wu, Runze, Zhou, Hongyou, Zhang, Kai, Li, Ke, Lin, Wenzheng, Shi, Qin, Chen, Hao, Lv, Shan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10367550/
https://www.ncbi.nlm.nih.gov/pubmed/37496992
http://dx.doi.org/10.7150/ijbs.82933