Lats2 deficiency protects the heart against myocardial infarction by reducing inflammation and inhibiting mitochondrial fission and STING/p65 signaling

Large tumor suppressor kinase 2 (Lats2) is a member of the Hippo pathway, a critical regulator of organ size. Since Lats2 activity may trigger mitochondrial dysfunction, a key pathogenic factor in acute myocardial infarction (AMI), this study sought to investigate whether Lats2 deletion confers card...

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Detalles Bibliográficos
Autores principales: Liu, Libao, Huang, Shuai, Du, Yingzhen, Zhou, Hao, Zhang, Kai, He, Jinyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2023
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10367568/
https://www.ncbi.nlm.nih.gov/pubmed/37497006
http://dx.doi.org/10.7150/ijbs.84426

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10367568/
https://www.ncbi.nlm.nih.gov/pubmed/37497006
http://dx.doi.org/10.7150/ijbs.84426

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