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Estradiol- and Progesterone-Associated Changes in microRNA-Induced Silencing and Reduced Antiseizure Efficacy of an Antagomir in Female Mice

About one-third of individuals living with epilepsy have treatment-resistant seizures. Alternative therapeutic strategies are thus urgently needed. One potential novel treatment target is miRNA-induced silencing, which is differentially regulated in epilepsy. Inhibitors (antagomirs) of specific micr...

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Detalles Bibliográficos
Autores principales: Tiwari, Durgesh, Rajathi, Valerine, Rymer, Jeffrey K., Beasley, Lindsay N., McGann, Amanda M., Bunk, Alexander T., Parkins, Emma V., Rice, McKenzie F., Smith, Katie E., Ritter, David M., White, Angela R., Doerning, Carolyn M., Gross, Christina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10368146/
https://www.ncbi.nlm.nih.gov/pubmed/37433683
http://dx.doi.org/10.1523/ENEURO.0047-22.2023