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Estradiol- and Progesterone-Associated Changes in microRNA-Induced Silencing and Reduced Antiseizure Efficacy of an Antagomir in Female Mice
About one-third of individuals living with epilepsy have treatment-resistant seizures. Alternative therapeutic strategies are thus urgently needed. One potential novel treatment target is miRNA-induced silencing, which is differentially regulated in epilepsy. Inhibitors (antagomirs) of specific micr...
Autores principales: | Tiwari, Durgesh, Rajathi, Valerine, Rymer, Jeffrey K., Beasley, Lindsay N., McGann, Amanda M., Bunk, Alexander T., Parkins, Emma V., Rice, McKenzie F., Smith, Katie E., Ritter, David M., White, Angela R., Doerning, Carolyn M., Gross, Christina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Society for Neuroscience
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10368146/ https://www.ncbi.nlm.nih.gov/pubmed/37433683 http://dx.doi.org/10.1523/ENEURO.0047-22.2023 |
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