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Gene-regulation modules in nonalcoholic fatty liver disease revealed by single-nucleus ATAC-seq

We investigated the progression of nonalcoholic fatty liver disease from fatty liver to steatohepatitis using single-nucleus and bulk ATAC-seq on the livers of rats fed a high-fat diet (HFD). Rats fed HFD for 4 wk developed fatty liver, and those fed HFD for 8 wk further progressed to steatohepatiti...

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Detalles Bibliográficos
Autores principales: Takeuchi, Fumihiko, Liang, Yi-Qiang, Shimizu-Furusawa, Hana, Isono, Masato, Ang, Mia Yang, Mori, Kotaro, Mori, Taizo, Kakazu, Eiji, Yoshio, Sachiyo, Kato, Norihiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10368228/
https://www.ncbi.nlm.nih.gov/pubmed/37491046
http://dx.doi.org/10.26508/lsa.202301988