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PU.1 is required to restrain myelopoiesis during chronic inflammatory stress

Chronic inflammation is a common feature of aging and numerous diseases such as diabetes, obesity, and autoimmune syndromes and has been linked to the development of hematological malignancy. Blood-forming hematopoietic stem cells (HSC) can contribute to these diseases via the production of tissue-d...

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Detalles Bibliográficos
Autores principales: Chavez, James S., Rabe, Jennifer L., Niño, Katia E., Wells, Harrison H., Gessner, Rachel L., Mills, Taylor S., Hernandez, Giovanny, Pietras, Eric M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10368259/
https://www.ncbi.nlm.nih.gov/pubmed/37497478
http://dx.doi.org/10.3389/fcell.2023.1204160