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The respiratory syncytial virus M2-2 protein is targeted for proteasome degradation and inhibits translation and stress granules assembly

The M2-2 protein from the respiratory syncytial virus (RSV) is a 10 kDa protein expressed by the second ORF of the viral gene M2. During infection, M2-2 has been described as the polymerase cofactor responsible for promoting genome replication, which occurs by the induction of changes in interaction...

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Detalles Bibliográficos
Autores principales: Scudero, Orlando Bonito, Santiago, Verônica Feijoli, Palmisano, Giuseppe, Simabuco, Fernando Moreira, Ventura, Armando Morais
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10368288/
https://www.ncbi.nlm.nih.gov/pubmed/37490507
http://dx.doi.org/10.1371/journal.pone.0289100