Loss of STING in parkin mutant flies suppresses muscle defects and mitochondria damage

The early pathogenesis and underlying molecular causes of motor neuron degeneration in Parkinson’s Disease (PD) remains unresolved. In the model organism Drosophila melanogaster, loss of the early-onset PD gene parkin (the ortholog of human PRKN) results in impaired climbing ability, damage to the i...

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Detalles Bibliográficos
Autores principales: Moehlman, Andrew T., Kanfer, Gil, Youle, Richard J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10368295/
https://www.ncbi.nlm.nih.gov/pubmed/37440574
http://dx.doi.org/10.1371/journal.pgen.1010828

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10368295/
https://www.ncbi.nlm.nih.gov/pubmed/37440574
http://dx.doi.org/10.1371/journal.pgen.1010828

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