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Melanocortin 1 receptor regulates cholesterol and bile acid metabolism in the liver

Melanocortin 1 receptor (MC1-R) is widely expressed in melanocytes and leukocytes and is thus strongly implicated in the regulation of skin pigmentation and inflammation. MC1-R has also been found in the rat and human liver, but its functional role has remained elusive. We hypothesized that MC1-R is...

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Detalles Bibliográficos
Autores principales: Thapa, Keshav, Kadiri, James J, Saukkonen, Karla, Pennanen, Iida, Ghimire, Bishwa, Cai, Minying, Savontaus, Eriika, Rinne, Petteri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10368426/
https://www.ncbi.nlm.nih.gov/pubmed/37490042
http://dx.doi.org/10.7554/eLife.84782