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An Exploratory Study on the Contractile Effects of Hydroxy-α-Sanshool and Hydroxy-β-Sanshool, the Active Ingredients of Daikenchuto, on the Internal Anal Sphincter

OBJECTIVES: Daikenchuto (DKT) enhances the contraction of the internal anal sphincter (IAS) in patients with constipation and fecal incontinence; however, the mechanism of its action is unknown. We investigated the effects of the active ingredients of DKT (hydroxy-α-sanshool (HAS) and hydroxy-β-sans...

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Detalles Bibliográficos
Autores principales: Maeda, Kotaro, Sasaki, Toshinobu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japan Society of Coloproctology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10368429/
https://www.ncbi.nlm.nih.gov/pubmed/37496571
http://dx.doi.org/10.23922/jarc.2023-001