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Upregulation of the CD155-CD226 Axis Is Associated With Muscle Inflammation and Disease Severity in Idiopathic Inflammatory Myopathies

BACKGROUND AND OBJECTIVES: The CD155-CD226/T-cell Ig and immunoreceptor tyrosine-based inhibitory motif (ITIM) domain (TIGIT) pathway plays a critical role in regulating T-cell responses and is being targeted clinically. However, research on the role of this pathway in autoimmune diseases is limited...

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Detalles Bibliográficos
Autores principales: Li, Wenli, Deng, Chuiwen, Yang, Hanbo, Tian, Xiaolan, Chen, Lida, Liu, Qingyan, Gao, Chang, Lu, Xin, Wang, Guochun, Peng, Qinglin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10368451/
https://www.ncbi.nlm.nih.gov/pubmed/37491355
http://dx.doi.org/10.1212/NXI.0000000000200143