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Integration of nuclear Ca(2+) transients and subnuclear protein shuttling provides a novel mechanism for the regulation of CREB-dependent gene expression
Nuclear Ca(2+) waves elicited by NMDAR and L-type voltage-gated Ca(2+)-channels as well as protein transport from synapse-to-nucleus are both instrumental in control of plasticity-related gene expression. At present it is not known whether fast [Ca(2+)](n) transients converge in the nucleus with sig...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer International Publishing
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10368568/ https://www.ncbi.nlm.nih.gov/pubmed/37491479 http://dx.doi.org/10.1007/s00018-023-04876-8 |