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Pan-cancer structurome reveals overrepresentation of beta sandwiches and underrepresentation of alpha helical domains
The recent progress in the prediction of protein structures marked a historical milestone. AlphaFold predicted 200 million protein models with an accuracy comparable to experimental methods. Protein structures are widely used to understand evolution and to identify potential drug targets for the tre...
Autores principales: | Medvedev, Kirill E., Schaeffer, R. Dustin, Chen, Kenneth S., Grishin, Nick V. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10368619/ https://www.ncbi.nlm.nih.gov/pubmed/37491511 http://dx.doi.org/10.1038/s41598-023-39273-5 |
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