Genetically diverse mouse models of SARS-CoV-2 infection reproduce clinical variation in type I interferon and cytokine responses in COVID-19

Inflammation in response to severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection drives severity of coronavirus disease 2019 (COVID-19) and is influenced by host genetics. To understand mechanisms of inflammation, animal models that reflect genetic diversity and clinical outcomes o...

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Detalles Bibliográficos
Autores principales: Robertson, Shelly J., Bedard, Olivia, McNally, Kristin L., Shaia, Carl, Clancy, Chad S., Lewis, Matthew, Broeckel, Rebecca M., Chiramel, Abhilash I., Shannon, Jeffrey G., Sturdevant, Gail L., Rosenke, Rebecca, Anzick, Sarah L., Forte, Elvira, Preuss, Christoph, Baker, Candice N., Harder, Jeffrey M., Brunton, Catherine, Munger, Steven, Bruno, Daniel P., Lack, Justin B., Leung, Jacqueline M., Shamsaddini, Amirhossein, Gardina, Paul, Sturdevant, Daniel E., Sun, Jian, Martens, Craig, Holland, Steven M., Rosenthal, Nadia A., Best, Sonja M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10368652/
https://www.ncbi.nlm.nih.gov/pubmed/37491352
http://dx.doi.org/10.1038/s41467-023-40076-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10368652/
https://www.ncbi.nlm.nih.gov/pubmed/37491352
http://dx.doi.org/10.1038/s41467-023-40076-5

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