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Comparative effects of CFTR modulators on phagocytic, metabolic and inflammatory profiles of CF and nonCF macrophages

Macrophage dysfunction has been well-described in Cystic Fibrosis (CF) and may contribute to bacterial persistence in the lung. Whether CF macrophage dysfunction is related directly to Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) in macrophages or an indirect consequence of chronic inf...

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Detalles Bibliográficos
Autores principales: Aridgides, Daniel S., Mellinger, Diane L., Gwilt, Lorraine L., Hampton, Thomas H., Mould, Dallas L., Hogan, Deborah A., Ashare, Alix
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10368712/
https://www.ncbi.nlm.nih.gov/pubmed/37491532
http://dx.doi.org/10.1038/s41598-023-38300-9