Cargando…
Comparative effects of CFTR modulators on phagocytic, metabolic and inflammatory profiles of CF and nonCF macrophages
Macrophage dysfunction has been well-described in Cystic Fibrosis (CF) and may contribute to bacterial persistence in the lung. Whether CF macrophage dysfunction is related directly to Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) in macrophages or an indirect consequence of chronic inf...
Autores principales: | Aridgides, Daniel S., Mellinger, Diane L., Gwilt, Lorraine L., Hampton, Thomas H., Mould, Dallas L., Hogan, Deborah A., Ashare, Alix |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10368712/ https://www.ncbi.nlm.nih.gov/pubmed/37491532 http://dx.doi.org/10.1038/s41598-023-38300-9 |
Ejemplares similares
-
Altered iron metabolism in cystic fibrosis macrophages: the impact of CFTR modulators and implications for Pseudomonas aeruginosa survival
por: Hazlett, H. F., et al.
Publicado: (2020) -
CF Fungal Disease in the Age of CFTR Modulators
por: Bercusson, Amelia, et al.
Publicado: (2021) -
ScRNA-seq expression of IFI27 and APOC2 identifies four alveolar macrophage superclusters in healthy BALF
por: Li, Xin, et al.
Publicado: (2022) -
Functional and metabolic impairment in cigarette smoke-exposed macrophages is tied to oxidative stress
por: Aridgides, Daniel S., et al.
Publicado: (2019) -
Macrophages from gut-corrected CF mice express human CFTR and lack a pro-inflammatory phenotype
por: Gillan, Jonathan L, et al.
Publicado: (2022)