Sequestration of histidine kinases by non-cognate response regulators establishes a threshold level of stimulation for bacterial two-component signaling

Bacterial two-component systems (TCSs) consist of a sensor histidine kinase (HK) that perceives a specific signal, and a cognate response regulator (RR) that modulates the expression of target genes. Positive autoregulation improves TCS sensitivity to stimuli, but may trigger disproportionately larg...

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Detalles Bibliográficos
Autores principales: Sankhe, Gaurav D., Raja, Rubesh, Singh, Devendra Pratap, Bheemireddy, Sneha, Rana, Subinoy, Athira, P. J., Dixit, Narendra M., Saini, Deepak Kumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10368727/
https://www.ncbi.nlm.nih.gov/pubmed/37491529
http://dx.doi.org/10.1038/s41467-023-40095-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10368727/
https://www.ncbi.nlm.nih.gov/pubmed/37491529
http://dx.doi.org/10.1038/s41467-023-40095-2

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