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Sequestration of histidine kinases by non-cognate response regulators establishes a threshold level of stimulation for bacterial two-component signaling
Bacterial two-component systems (TCSs) consist of a sensor histidine kinase (HK) that perceives a specific signal, and a cognate response regulator (RR) that modulates the expression of target genes. Positive autoregulation improves TCS sensitivity to stimuli, but may trigger disproportionately larg...
Autores principales: | Sankhe, Gaurav D., Raja, Rubesh, Singh, Devendra Pratap, Bheemireddy, Sneha, Rana, Subinoy, Athira, P. J., Dixit, Narendra M., Saini, Deepak Kumar |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10368727/ https://www.ncbi.nlm.nih.gov/pubmed/37491529 http://dx.doi.org/10.1038/s41467-023-40095-2 |
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