Zinc-finger BED domains drive the formation of the active Hermes transpososome by asymmetric DNA binding

The Hermes DNA transposon is a member of the eukaryotic hAT superfamily, and its transposase forms a ring-shaped tetramer of dimers. Our investigation, combining biochemical, crystallography and cryo-electron microscopy, and in-cell assays, shows that the full-length Hermes octamer extensively inter...

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Detalles Bibliográficos
Autores principales: Lannes, Laurie, Furman, Christopher M., Hickman, Alison B., Dyda, Fred
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10368747/
https://www.ncbi.nlm.nih.gov/pubmed/37491363
http://dx.doi.org/10.1038/s41467-023-40210-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10368747/
https://www.ncbi.nlm.nih.gov/pubmed/37491363
http://dx.doi.org/10.1038/s41467-023-40210-3

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