Cargando…
Zinc-finger BED domains drive the formation of the active Hermes transpososome by asymmetric DNA binding
The Hermes DNA transposon is a member of the eukaryotic hAT superfamily, and its transposase forms a ring-shaped tetramer of dimers. Our investigation, combining biochemical, crystallography and cryo-electron microscopy, and in-cell assays, shows that the full-length Hermes octamer extensively inter...
| Autores principales: | , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2023
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10368747/ https://www.ncbi.nlm.nih.gov/pubmed/37491363 http://dx.doi.org/10.1038/s41467-023-40210-3 |