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Serum from half of patients with immune thrombocytopenia trigger macrophage phagocytosis of platelets

Humoral antiplatelet factors, such as autoantibodies, are thought to primarily clear platelets by triggering macrophage phagocytosis in immune thrombocytopenia (ITP). However, there are few studies characterizing the capacity and mechanisms of humoral factor–triggered macrophage phagocytosis of plat...

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Detalles Bibliográficos
Autores principales: Norris, Peter A. A., Tawhidi, Zoya, Sachs, Ulrich J., Cserti-Gazdewich, Christine M., Lin, Yulia, Callum, Jeannie, Gil Gonzalez, Lazaro, Shan, Yuexin, Branch, Donald R., Lazarus, Alan H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society of Hematology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10368862/
https://www.ncbi.nlm.nih.gov/pubmed/37042934
http://dx.doi.org/10.1182/bloodadvances.2022009423