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Computational study of SENP1 in cancer by novel natural compounds and ZINC database screening

Introduction: Sentrin-specific protease 1 (SENP1) is a protein whose main function is deSUMOylation. SENP1 inhibits apoptosis, and increases angiogenesis, estrogen and androgen receptor transcription and c-Jun transcription factor, proliferation, growth, cell migration, and invasion of cancer. The i...

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Detalles Bibliográficos
Autores principales: Taghvaei, Somayye, Taghvaei, Alireza, Anvar, Mohammad Saberi, Guo, Chun, Sabouni, Farzaneh, Minuchehr, Zarrin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10368881/
https://www.ncbi.nlm.nih.gov/pubmed/37502217
http://dx.doi.org/10.3389/fphar.2023.1144632