Emerging EGFR-Mutated Subclones in a Patient With Metastatic ALK-Rearranged Lung Adenocarcinoma Treated With ALK-Targeted Therapy: A Case Report

We report a case of pathologically confirmed ALK-rearranged metastatic lung adenocarcinoma with emergence of EGFR L858R mutation on disease progression after two lines of treatment with ALK inhibitors. At initial diagnosis, tumoral ALK expression was detected without EGFR mutation by standard allele...

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Detalles Bibliográficos
Autores principales: Leung, Jackson Ka Chun, Kwok, Wang Chun, Leung, Arthur Chun Fung, Tsui, Po, Ho, James Chung-Man
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10368895/
https://www.ncbi.nlm.nih.gov/pubmed/37502466
http://dx.doi.org/10.1016/j.jtocrr.2023.100542

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10368895/
https://www.ncbi.nlm.nih.gov/pubmed/37502466
http://dx.doi.org/10.1016/j.jtocrr.2023.100542

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