A defined method for differentiating human iPSCs into midbrain dopaminergic progenitors that safely restore motor deficits in Parkinson’s disease

BACKGROUND: Parkinson’s disease (PD) is a progressive neurodegenerative condition that primarily affects motor functions; it is caused by the loss of midbrain dopaminergic (mDA) neurons. The therapeutic effects of transplanting human-induced pluripotent stem cell (iPSC)-derived mDA neural progenitor...

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Detalles Bibliográficos
Autores principales: Nakamura, Ryota, Nonaka, Risa, Oyama, Genko, Jo, Takayuki, Kamo, Hikaru, Nuermaimaiti, Maierdanjiang, Akamatsu, Wado, Ishikawa, Kei-ichi, Hattori, Nobutaka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10368972/
https://www.ncbi.nlm.nih.gov/pubmed/37502682
http://dx.doi.org/10.3389/fnins.2023.1202027

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10368972/
https://www.ncbi.nlm.nih.gov/pubmed/37502682
http://dx.doi.org/10.3389/fnins.2023.1202027

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