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Protective efficacy of Toxoplasma gondii GRA12 or GRA7 recombinant proteins encapsulated in PLGA nanoparticles against acute Toxoplasma gondii infection in mice

BACKGROUND: Toxoplasma gondii is an apicomplexan parasite that affects the health of humans and livestock, and an effective vaccine is urgently required. Nanoparticles can modulate and improve cellular and humoral immune responses. METHODS: In the current study, poly (D, L-lactic-co-glycolic acid) (...

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Detalles Bibliográficos
Autores principales: Sun, Hong-chao, Deng, Pu-ming, Fu, Yuan, Deng, Jin-hua, Xie, Rong-hui, Huang, Jing, Qi, Meng, Shi, Tuan-yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10368986/
https://www.ncbi.nlm.nih.gov/pubmed/37502604
http://dx.doi.org/10.3389/fcimb.2023.1209755