Blocking soluble Fas Ligand ameliorates pemphigus: PC111 efficacy in ex-vivo human pemphigus models

Pemphigus is a life-threatening, chronic, autoimmune bullous disease affecting both the skin and the mucous membranes. Based on the mainstream concept that blister formation occurs upon binding of autoantibodies to their antigen proteins (desmoglein1, DSG1 and desmoglein3, DSG3), current therapies m...

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Detalles Bibliográficos
Autores principales: Lotti, Roberta, Hundt, Jennifer E., Ludwig, Ralf J., Bennett, Brydon, Amato, Antonino, Marconi, Alessandra, Pincelli, Carlo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10368993/
https://www.ncbi.nlm.nih.gov/pubmed/37503332
http://dx.doi.org/10.3389/fimmu.2023.1193032

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10368993/
https://www.ncbi.nlm.nih.gov/pubmed/37503332
http://dx.doi.org/10.3389/fimmu.2023.1193032

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