Radiolabelling of peptides with tetrazine ligation based on the inverse electron-demand Diels–Alder reaction: rapid, catalyst-free and mild conversion of 1,4-dihydropyridazines to pyridazines

Click chemistry reactions, such as the tetrazine ligation, based on the inverse-electron demand Diels–Alder (IEDDA), are chemoselective cycloaddition reactions widely used for chemical modifications and synthesis of biomolecule-based radiopharmaceuticals for positron emission tomography (PET). The r...

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Detalles Bibliográficos
Autores principales: Otaru, Sofia, Martinmäki, Tatu, Kuurne, Iida, Paulus, Andreas, Helariutta, Kerttuli, Sarparanta, Mirkka, Airaksinen, Anu J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2023
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10369045/
https://www.ncbi.nlm.nih.gov/pubmed/37501774
http://dx.doi.org/10.1039/d3ra02807k

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10369045/
https://www.ncbi.nlm.nih.gov/pubmed/37501774
http://dx.doi.org/10.1039/d3ra02807k

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