PARPi Decreased Primary Ovarian Cancer Organoid Growth Through Early Apoptosis and Base Excision Repair Pathway

Ovarian cancer (OC), particularly high-grade serous cancer (HGSC), is the leading cause of mortality among gynecological cancers owing to the treatment difficulty and high recurrence probability. As therapeutic drugs approved for OC, poly ADP-ribose polymerase inhibitors (PARPi) lead to synthetic le...

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Detalles Bibliográficos
Autores principales: Cao, Qi, Li, Lanyang, Zhao, Yuqing, Wang, Chen, Shi, Yanghua, Tao, Xiang, Cai, Chunhui, Han, Xin-Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10369085/
https://www.ncbi.nlm.nih.gov/pubmed/37488947
http://dx.doi.org/10.1177/09636897231187996

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10369085/
https://www.ncbi.nlm.nih.gov/pubmed/37488947
http://dx.doi.org/10.1177/09636897231187996

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