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PARPi Decreased Primary Ovarian Cancer Organoid Growth Through Early Apoptosis and Base Excision Repair Pathway
Ovarian cancer (OC), particularly high-grade serous cancer (HGSC), is the leading cause of mortality among gynecological cancers owing to the treatment difficulty and high recurrence probability. As therapeutic drugs approved for OC, poly ADP-ribose polymerase inhibitors (PARPi) lead to synthetic le...
Autores principales: | Cao, Qi, Li, Lanyang, Zhao, Yuqing, Wang, Chen, Shi, Yanghua, Tao, Xiang, Cai, Chunhui, Han, Xin-Xin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10369085/ https://www.ncbi.nlm.nih.gov/pubmed/37488947 http://dx.doi.org/10.1177/09636897231187996 |
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