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Effects of Tirzepatide Versus Insulin Glargine on Cystatin C–Based Kidney Function: A SURPASS-4 Post Hoc Analysis

OBJECTIVE: Tirzepatide reduces HbA(1c) and body weight, and creatinine-based estimated glomerular filtration rate (eGFR) decline. Unlike creatine-derived eGFR (eGFR-creatinine), cystatin C–derived eGFR (eGFR-cystatin C) is unaffected by muscle mass changes. We assessed effects of tirzepatide on eGFR...

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Detalles Bibliográficos
Autores principales: Heerspink, Hiddo J.L., Sattar, Naveed, Pavo, Imre, Haupt, Axel, Duffin, Kevin L., Yang, Zhengyu, Wiese, Russell J., Wilson, Jonathan M., Hemmingway, Andrea, Cherney, David Z.I., Tuttle, Katherine R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10369133/
https://www.ncbi.nlm.nih.gov/pubmed/37267479
http://dx.doi.org/10.2337/dc23-0261