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The GHB analogue HOCPCA improves deficits in cognition and sensorimotor function after MCAO via CaMKIIα

Ca(2+)/calmodulin-dependent protein kinase II alpha (CaMKIIα) is a major contributor to physiological and pathological glutamate-mediated Ca(2+) signals, and its involvement in various critical cellular pathways demands specific pharmacological strategies. We recently presented γ-hydroxybutyrate (GH...

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Detalles Bibliográficos
Autores principales: Griem-Krey, Nane, Klein, Anders B, Clausen, Bettina H, Namini, Mathias RJ, Nielsen, Pernille V, Bhuiyan, Mozammel, Nagaraja, Raghavendra Y, De Silva, T Michael, Sobey, Christopher G, Cheng, Heung-Chin, Orset, Cyrille, Vivien, Denis, Lambertsen, Kate L, Clarkson, Andrew N, Wellendorph, Petrine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10369146/
https://www.ncbi.nlm.nih.gov/pubmed/37026450
http://dx.doi.org/10.1177/0271678X231167920