Symmetry Breaking of Human Pluripotent Stem Cells (hPSCs) in Micropattern Generates a Polarized Spinal Cord‐Like Organoid (pSCO) with Dorsoventral Organization

Axis formation and related spatial patterning are initiated by symmetry breaking during development. A geometrically confined culture of human pluripotent stem cells (hPSCs) mimics symmetry breaking and cell patterning. Using this, polarized spinal cord organoids (pSCOs) with a self‐organized dorsov...

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Detalles Bibliográficos
Autores principales: Seo, Kyubin, Cho, Subin, Shin, Hyogeun, Shin, Aeri, Lee, Ju‐Hyun, Kim, June Hoan, Lee, Boram, Jang, Hwanseok, Kim, Youngju, Cho, Hyo Min, Park, Yongdoo, Kim, Hee Youn, Lee, Taeseob, Park, Woong‐Yang, Kim, Yong Jun, Yang, Esther, Geum, Dongho, Kim, Hyun, Cho, Il‐Joo, Lee, Sanghyuk, Ryu, Jae Ryun, Sun, Woong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10369253/
https://www.ncbi.nlm.nih.gov/pubmed/37170679
http://dx.doi.org/10.1002/advs.202301787

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10369253/
https://www.ncbi.nlm.nih.gov/pubmed/37170679
http://dx.doi.org/10.1002/advs.202301787

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