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Identification and Characterization of the Wilms Tumor Cancer Stem Cell

A nephrogenic progenitor cell (NP) with cancer stem cell characteristics driving Wilms tumor (WT) using spatial transcriptomics, bulk and single cell RNA sequencing, and complementary in vitro and transplantation experiments is identified and characterized. NP from WT samples with NP from the develo...

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Detalles Bibliográficos
Autores principales: Petrosyan, Astgik, Villani, Valentina, Aguiari, Paola, Thornton, Matthew E., Wang, Yizhou, Rajewski, Alex, Zhou, Shengmei, Cravedi, Paolo, Grubbs, Brendan H., De Filippo, Roger E., Sedrakyan, Sargis, Lemley, Kevin V., Csete, Marie, Da Sacco, Stefano, Perin, Laura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10369255/
https://www.ncbi.nlm.nih.gov/pubmed/37114795
http://dx.doi.org/10.1002/advs.202206787