PERK‐Mediated Cholesterol Excretion from IDH Mutant Glioma Determines Anti‐Tumoral Polarization of Microglia

Isocitrate dehydrogenase (IDH) mutation, a known pathologic classifier, initiates metabolic reprogramming in glioma cells and has been linked to the reaction status of glioma‐associated microglia/macrophages (GAMs). However, it remains unclear how IDH genotypes contribute to GAM phenotypes. Here, it...

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Detalles Bibliográficos
Autores principales: Wang, Tao, Zhou, Yunxia, Fan, Yunping, Duan, Hao, Guo, Xiaoyu, Chang, Jinlong, Jiang, Youheng, Li, Changxue, Fu, Zhang, Gao, Yunfei, Guo, Xiaoran, Sidlauskas, Kastytis, He, Zhenqiang, Da Costa, Clive, Sheng, Xia, Wu, Dinglan, Yuan, Jinqiu, Li, Huiliang, He, Yulong, Mou, Yonggao, Li, Ningning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10369258/
https://www.ncbi.nlm.nih.gov/pubmed/37166058
http://dx.doi.org/10.1002/advs.202205949

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10369258/
https://www.ncbi.nlm.nih.gov/pubmed/37166058
http://dx.doi.org/10.1002/advs.202205949

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