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Targeting L‐Selectin Lymphocytes to Deliver Immunosuppressive Drug in Lymph Nodes for Durable Multiple Sclerosis Treatment

Inflammation induced by autoreactive CD4(+) T lymphocytes is a major factor in the pathogenesis of multiple sclerosis (MS). Immunosuppressive drugs, such as FTY720, are subsequently developed to prevent the migration of CD4(+) T lymphocytes to the central nervous system (CNS). However, these immunos...

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Detalles Bibliográficos
Autores principales: Zhao, Yipeng, Zhang, Jie, Cheng, Xi, Huang, Wenping, Shen, Shishi, Wu, Shilin, Huang, Yiying, Nie, Guangjun, Wang, Hai, Qiu, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10369270/
https://www.ncbi.nlm.nih.gov/pubmed/37170724
http://dx.doi.org/10.1002/advs.202300738