Cargando…
Targeting L‐Selectin Lymphocytes to Deliver Immunosuppressive Drug in Lymph Nodes for Durable Multiple Sclerosis Treatment
Inflammation induced by autoreactive CD4(+) T lymphocytes is a major factor in the pathogenesis of multiple sclerosis (MS). Immunosuppressive drugs, such as FTY720, are subsequently developed to prevent the migration of CD4(+) T lymphocytes to the central nervous system (CNS). However, these immunos...
Autores principales: | Zhao, Yipeng, Zhang, Jie, Cheng, Xi, Huang, Wenping, Shen, Shishi, Wu, Shilin, Huang, Yiying, Nie, Guangjun, Wang, Hai, Qiu, Wei |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10369270/ https://www.ncbi.nlm.nih.gov/pubmed/37170724 http://dx.doi.org/10.1002/advs.202300738 |
Ejemplares similares
-
A cell-extrinsic ligand acquired by activated T cells in lymph node can bridge L-selectin and P-selectin
por: Carlow, Douglas A., et al.
Publicado: (2018) -
Entry of naive CD4 T cells into peripheral lymph nodes requires L- selectin
Publicado: (1994) -
Vascular Adhesion Protein 1 (VAP-1) Mediates Lymphocyte Subtype-specific, Selectin-independent Recognition of Vascular Endothelium in Human Lymph Nodes
por: Salmi, Marko, et al.
Publicado: (1997) -
Suppression of tumor formation in lymph nodes by L-selectin–mediated natural killer cell recruitment
por: Chen, Shihao, et al.
Publicado: (2005) -
L-selectin-dependent and -independent homing of naïve lymphocytes through the lung draining lymph node support T cell response to pulmonary Mycobacterium tuberculosis infection
por: Daniel, Lina, et al.
Publicado: (2023)