Elevated PDGF‐BB from Bone Impairs Hippocampal Vasculature by Inducing PDGFRβ Shedding from Pericytes

Evidence suggests a unique association between bone aging and neurodegenerative/cerebrovascular disorders. However, the mechanisms underlying bone‐brain interplay remain elusive. Here platelet‐derived growth factor‐BB (PDGF‐BB) produced by preosteoclasts in bone is reported to promote age‐associated...

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Detalles Bibliográficos
Autores principales: Liu, Guanqiao, Wang, Jiekang, Wei, Zhiliang, Fang, Ching‐Lien, Shen, Ke, Qian, Cheng, Qi, Cheng, Li, Tong, Gao, Peisong, Wong, Philip C., Lu, Hanzhang, Cao, Xu, Wan, Mei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10369301/
https://www.ncbi.nlm.nih.gov/pubmed/37102631
http://dx.doi.org/10.1002/advs.202206938

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10369301/
https://www.ncbi.nlm.nih.gov/pubmed/37102631
http://dx.doi.org/10.1002/advs.202206938

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