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Thimet oligopeptidase as a potential CSF biomarker for Alzheimer's disease: A cross‐platform validation study

INTRODUCTION: Our previous antibody‐based cerebrospinal fluid (CSF) proteomics study showed that Thimet oligopeptidase (THOP1), an amyloid beta (Aβ) neuropeptidase, was increased in mild cognitive impairment with amyloid pathology (MCI‐Aβ+) and Alzheimer's disease (AD) dementia compared with co...

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Detalles Bibliográficos
Autores principales: Hok‐A‐Hin, Yanaika S., Bolsewig, Katharina, Ruiters, Daimy N., Lleó, Alberto, Alcolea, Daniel, Lemstra, Afina W., van der Flier, Wiesje M., Teunissen, Charlotte E., del Campo, Marta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10369371/
https://www.ncbi.nlm.nih.gov/pubmed/37502019
http://dx.doi.org/10.1002/dad2.12456