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Thimet oligopeptidase as a potential CSF biomarker for Alzheimer's disease: A cross‐platform validation study
INTRODUCTION: Our previous antibody‐based cerebrospinal fluid (CSF) proteomics study showed that Thimet oligopeptidase (THOP1), an amyloid beta (Aβ) neuropeptidase, was increased in mild cognitive impairment with amyloid pathology (MCI‐Aβ+) and Alzheimer's disease (AD) dementia compared with co...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10369371/ https://www.ncbi.nlm.nih.gov/pubmed/37502019 http://dx.doi.org/10.1002/dad2.12456 |