High Density of N- and O-Glycosylation Shields and Defines the Structural Dynamics of the Intrinsically Disordered Ectodomain of Receptor-type Protein Tyrosine Phosphatase Alpha

[Image: see text] The intracellular phosphatase domain of the receptor-type protein tyrosine phosphatase alpha (PTPRA) is known to regulate various signaling pathways related to cell adhesion through c-Src kinase activation. In contrast, the functional significance of its relatively short, intrinsic...

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Detalles Bibliográficos
Autores principales: Chien, Yu-Chun, Wang, Yong-Sheng, Sridharan, Deepa, Kuo, Chu-Wei, Chien, Chih-Ta, Uchihashi, Takayuki, Kato, Koichi, Angata, Takashi, Meng, Tzu-Ching, Hsu, Shang-Te Danny, Khoo, Kay-Hooi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10369406/
https://www.ncbi.nlm.nih.gov/pubmed/37502146
http://dx.doi.org/10.1021/jacsau.3c00124

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10369406/
https://www.ncbi.nlm.nih.gov/pubmed/37502146
http://dx.doi.org/10.1021/jacsau.3c00124

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