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S373P Mutation Stabilizes the Receptor-Binding Domain of the Spike Protein in Omicron and Promotes Binding

[Image: see text] A cluster of several newly occurring mutations on Omicron is found at the β-core region of the spike protein’s receptor-binding domain (RBD), where mutation rarely happened before. Notably, the binding of SARS-CoV-2 to human receptor ACE2 via RBD happens in a dynamic airway environ...

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Detalles Bibliográficos
Autores principales: Zheng, Bin, Xiao, Yuelong, Tong, Bei, Mao, Yutong, Ge, Rui, Tian, Fang, Dong, Xianchi, Zheng, Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10369413/
https://www.ncbi.nlm.nih.gov/pubmed/37502147
http://dx.doi.org/10.1021/jacsau.3c00142