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S373P Mutation Stabilizes the Receptor-Binding Domain of the Spike Protein in Omicron and Promotes Binding
[Image: see text] A cluster of several newly occurring mutations on Omicron is found at the β-core region of the spike protein’s receptor-binding domain (RBD), where mutation rarely happened before. Notably, the binding of SARS-CoV-2 to human receptor ACE2 via RBD happens in a dynamic airway environ...
Autores principales: | Zheng, Bin, Xiao, Yuelong, Tong, Bei, Mao, Yutong, Ge, Rui, Tian, Fang, Dong, Xianchi, Zheng, Peng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10369413/ https://www.ncbi.nlm.nih.gov/pubmed/37502147 http://dx.doi.org/10.1021/jacsau.3c00142 |
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