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Arginine Residues Modulate the Membrane Interactions of pHLIP Peptides
[Image: see text] Most processes at the water–membrane interface often involve protonation events in proteins or peptides that trigger important biological functions and events. This is the working principle behind the pHLIP peptide technology. A key titrating aspartate (Asp14 in wt) is required to...
Autores principales: | Silva, Tomás F. D., Visca, Hannah, Klumpp, Craig, Andreev, Oleg A., Reshetnyak, Yana K., Machuqueiro, Miguel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10369490/ https://www.ncbi.nlm.nih.gov/pubmed/37395685 http://dx.doi.org/10.1021/acs.jcim.3c00360 |
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