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Metformin increases pathological responses to rectal cancers with neoadjuvant chemoradiotherapy: a systematic review and meta-analysis

BACKGROUND: To summarize the chemo-radio effect of metformin in rectal cancers with neoadjuvant chemoradiotherapy on pathological response, tumor regression grade (TRG), and T/N downstaging. METHODS: PubMed, MEDLINE, Embase, and Cochrane Database of collected reviews were searched up to June 30, 202...

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Detalles Bibliográficos
Autores principales: Lai, I-Li, You, Jeng-Fu, Tsai, Wen-Sy, Hsu, Yu-Jen, Chern, Yih-Jong, Wu, Ming-Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10369710/
https://www.ncbi.nlm.nih.gov/pubmed/37491250
http://dx.doi.org/10.1186/s12957-023-03087-6